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Curriculum Vitae


John C. Conboy


Education:

1991  B.S., University of California, Davis, Davis, CA
1996  Ph.D., University of Oregon, Eugene, OR, Advisor: Prof. Geraldine L. Richmond

Professional Appointments:

1996 – 1997        Postdoctoral Associate, Prof. Paul F. Barbara,  Department of Chemistry, University of Minnesota, Minneapolis, MN
1998 – 1999        Postdoctoral Associate, Prof. S. Scott Saavedra, Department of Chemistry, University of Arizona, Tucson, AZ
1999 – 2000        National Institutes of Health (NIH) Post Doctoral Fellow (NRSA), Prof. S. Scott Saavedra, Department of Chemistry, University of Arizona, Tucson, AZ
2000 – 2003        Assistant Professor, Department of Chemistry, University of Utah, Salt Lake City, UT
2003 – 2006        Henry Eyring Assistant Professor, Department of Chemistry, University of Utah, Salt Lake City, UT
2006 – Present    Associate Professor, Henry Eyring Scholar, Department of Chemistry, University of Utah, Salt Lake City, UT

Honors and Awards:

1988                     CRC Freshman Chemistry Award
1992 – 1994        Department of Education (DOEd) Teacher/Scholar,  Graduate Assistance in Areas of National Need (GAANN)
1995                     Electrochemical Society, Energy Research Summer Fellowship, Department of Energy (DOE)
1999 – 2000        National Institutes of Health Post Doctoral Fellow, National Research Service Award (NRSA)
2003 – 2006        Henry Eyring Assistant Professor
2006 – present    Henry Eyring Scholar
2008                     Coblentz Society Craver Award in Applied Analytical Vibrational Spectroscopy


Professional Service:

Symposia Organization:

Symposium Organizer, “The Next Generation of Analytical Surface Scientist”, Northwest Regional American Chemical Society Meeting, Park City, Utah, 2008
Symposium Organizer, “Analytical Chemistry at the Biology Interface”, Northwest Regional American Chemical Society Meeting, Ogden, Utah, June 6-10, 2004
Chair/Organizer, Society of Western Analytical Professors, 37th Annual Meeting, Salt Lake City, Utah, January 16-17, 2004
Co-Organizer, “Nanoscale Organization via Self-Assembly", 77th American Chemical Society, Colloid and Surface Science Symposium, Georgia Tech, June 15-18, 2003.
Co-Organizer/Chair, “Spectroscopy at Interfaces”, 28th Federation of Analytical Chemistry and Spectroscopy Societies Meeting, Detroit, October 7-11, 2001.

Membership in Professional Societies:

American Chemical Society, Biophysical Society, Society for Applied Spectroscopy, The Coblentz Society

Scientific Review Service:

Accounts of Chemical Research, Analytical Chemistry, Applied Spectroscopy, Biophysical Chemistry, Biophysical Journal, Chemistry & Biology, Chemical Reviews, Journal of Chemical Physics, Journal of the American Chemical Society, Journal of Colloid and Interface Science, Journal of the Electrochemical Society, Journal of Physical Chemistry, Langmuir, Optics Communications, Optical Society of America, Proceedings of the National Academy of Science, Science

Grant Review:

National Science Foundation (NSF), National Institutes of Health (NIH), Petroleum Research Fund of the American Chemical Society, Department of Energy (DOE), Physics Research Council in the Netherlands


Departmental Service:

2000-2001             Graduate Education Committee
2004-2008             Graduate Education Committee
2000-2003             Analytical/Physical Seminar & Colloquium Committee
2001-2004             Analytical Chemistry Faculty Search Committee
2005-2006             Physical Chemistry Faculty Search Committee
2002-2003             Chair, Analytical Faculty Search Committee
2000-2005             Graduate Admissions Committee
2003-2008             Technical Support Committee (Optical)
2006-2007             Analytical Division Chair/Advisory Committee

University Service:

2001-2003             Undergraduate Education Curriculum Committee (Physical and Life Sciences)
2007-2010             Academic Senate
2007 – present      Director of the Masters of Science and Technology, Biotechnology Track
2008 – present      College of Science, State Science Initiative Task Force

Publications (in chronological order):

1) Conboy, J. C., Daschbach, J. L., Richmond, G. L., “Studies of the Alkane/Water Interface by Total Internal Reflection Second Harmonic Generation”, J. Phys. Chem., 1994, 98, 9688-9692.
2) Conboy, J. C., Daschbach, J. L., Richmond, G. L., “Total Internal Reflection Second-Harmonic Generation: Probing the Alkane/Water Interface”. Appl. Phys. A., 1994, 59, 623-629.
3) Messmer, M. C., Conboy, J. C., Richmond, G. L., “Resonant Sum Frequency Generation Studies of Surfactant Ordering at Oil-Water Interfaces", SPIE Proceedings, 1995, 2547, 135-41.
4) Messmer, M. C., Conboy, J. C., Richmond, G. L., “Observation of Molecular Ordering at the Liquid-Liquid Interface by Resonant Sum Frequency Generation”, J. Am. Chem. Soc., 1995, 117, 8039-8040.
    “Surfactant Molecules Ordering Viewed at Liquid/Liquid Interface”, C&E News, 1995, 73, 6-7.
5) Conboy, J. C., Richmond, G. L, “Total Internal Reflection Second Harmonic Generation from the Interface Between Two Immiscible Electrolyte Solutions”, Electrochimica Acta, 1995, 40, 2886-2886.
6) Conboy, J. C., Messmer, M. C., Richmond, G. L., “Investigation of Surfactant Conformation and Order at the Liquid/Liquid Interface by Total Internal Reflection Sum-Frequency Vibrational Spectroscopy”, J. Phys. Chem. B, 1995, 100, 7617-7622.
7) Rightor, E.G., Sehanobish, K., Young, G. P., Conboy, J. C., Wilchester, J. W., Bosnyak, C. P., “Real Time Study of Failure Events in Polymers, Part II”, J. Materials Sci., 1995, 30, 2083-2090.
8) Rightor, E. G., Young, G.P.,Sehanobish, K., Conboy, J. C., Bosnyak, C. P., “Real Time Study of Failure Events in Polymers, Part I”, J. Materials Sci., 1995, 30, 2077-2082.
9) Conboy, J. C., “Application of Second Harmonic Generation to the Investigation of the Electrochemical Interface between Two Immiscible Electrolyte Solutions”, Interface, 1996, 5, 49-52.
10) Conboy, J. C., Richmond, G. L, “Examination of the Electrochemical Interface Between Two Immiscible Electrolyte Solutions by Second Harmonic Generation”, J. Phys. Chem. B, 1997, 101, 983-990.
11) Conboy, J. C., Messmer, M. C., Walker, R. A., Richmond, G. L., “An Investigation of Surfactant Behavior at the Liquid/Liquid Interface with Sum-Frequency Vibrational Spectroscopy”, Progs. Colloid Polym. Sci., 1997, 103, 10-20.
12) Conboy, J. C., Messmer, M. C., Richmond, G. L., “Dependence of Alkyl Chain Conformation of Simple Ionic Surfactants on Head Group Functionality as Studied by Sum Frequency Vibrational Spectroscopy”, J. Phys. Chem. B, 1997, 101, 6724-6733.
13) Walker, R. A., Conboy, J. C., Richmond, G. L., “Molecular Structure and Ordering of Phospholipids at a Liquid/Liquid Interface”, Langmuir , 1997, 13, 3070-3073.
14) Conboy, J. C., Messmer, M. C., Richmond, G. L., “Effect of Alkyl Chain Length on the Conformation and Order of Simple Ionic Surfactants Adsorbed at the D2O-CCl4 Interface as Studied by Sum-Frequency Vibrational Spectroscopy”, Langmuir, 1998, 14, 6722-6727.
15) Conboy, J. C., Olson, E. J. C., Adams, D. M., Kerimo, J., Zaban, A., Gregg, B. A., Barbara, P. F., “Effect of Solvent Vapor Annealing on the Morphology and Photophysics of Molecular Semiconductor Thin Films”, J. Phys. Chem. B, 1998, 102, 4516-4525.
16) Conboy, J. C., McReynolds, K. D., Gervay-Hague, J., Saavedra, S. S., “Gp120 Binds Cooperatively to Several Biologically Relevant Glycosphingolipids: Quantitative Measurements at Equilibrium Using Total Internal Reflection Fluorescence Microscopy”, Angew. Chem. Int. Edit., 2000, 16, 2882-2884.
17) Ross, E. E., Bondurant, B., Spratt, T., Conboy, J. C., O’Brien, D. F., Saavedra, S. S., “Formation of Self-Assembled, Air-Stable Lipid Bilayer Membranes on Solid Supports”, Langmuir, 2001, 17, 2305-2307.
18) Conboy, J. C.; McReynolds, K. D.; Gervay-Hague, J., Saavedra, S. S., “Quantitative Measurements of Recombinant HIV Surface Glycoprotein 120 Binding to Several Glycosphingolipids Expressed in Planar Supported Lipid Bilayers”, J. Am. Chem. Soc., 2002, 124, 968-977.
19) McReynolds, K. D., Bhat, A., Conboy, J. C., Saavedra, S. S., Gervay-Hague, J., “Non-Natural Glycosphingolipids and Structurally Simpler Analogues Bind HIV-1 Recombinant Gp120”, Bioorgan. Med. Chem., 2002, 10, 625-637.
20) Conboy, J.C., Liu, S., O'Brien, D.F., Saavedra, S.S., “Planar Supported Bilayer Polymers Formed from Bis-Diene Lipids by Langmuir-Blodgett Deposition and UV Irradiation”, Biomacromolecules, 2003, 4, 841-849.
21) Kriech, M. A., Conboy, J.C., “Label-Free Chiral Detection of Melittin Binding to a Membrane”, J. Am. Chem. Soc., 2003, 125, 1148-1149.
22) Kriech, M. A., Conboy, J.C., “Measuring Melittin Binding to Planar Supported Lipid Bilayer by Chiral Second Harmonic Generation”, Anal. Chim. Acta, 2003, 496, (1-2), 143-153. (Invited Article)
23) Cherney, D. P., Conboy, J. C., Harris, J. M., "Optical-Trapping Raman Microscopy Detection of Single Unilamellar Lipid Vesicles", Anal. Chem. 2003, 75, 6621-6628.
24) Kriech, M. A., Conboy, J.C., “Counter-Propagating Second Harmonic Generation: A New Technique for the Investigation of Molecular Chirality at Interfaces”, Opt. Soc. Am. B, 2004, 21, 1013-1022.
25) Fitchett, B., Knepp, T., Conboy, J.C., “1-Alkyl-3-Methylimidazolium Bis(perfluoroalkylsulfonyl)imide Water-Immiscible Ionic Liquids: The Effect of Water on Electrochemical and Physical Properties”, J. Electrochem. Soc. 2004, 151, E219-E225.
26) Liu, J., Conboy, J. C., “Phase Transition of a Single Lipid Bilayer Measured by Sum-Frequency Vibrational Spectroscopy”, J. Am. Chem. Soc. 2004, 126, 8894-8895.
27) Liu, J., Conboy, J. C., “Direct Measurement of the Transbilayer Movement of Phospholipids by Sum-Frequency Vibrational Spectroscopy”, J. Am. Chem. Soc. 2004, 126, 8376-8377.
28) Fitchett, B., Conboy, J. C., “Structure of the Room-Temperature Ionic Liquid/SiO2 Interface Studied by Sum-Frequency Vibrational Spectroscopy”, J. Phys. Chem. B, 2004, 108, 20255-20262.
29) Kriech, M. A., Conboy, J.C., “Imaging Chirality with Surface Second Harmonic Generation Microscopy”, J. Am. Chem. Soc., 2005, 127, 2834-2835.
    “Imaging Chiral Molecules on Surfaces”, C&E News, 2005, 83, 32.
30) Kriech, M. A., Conboy, J.C., “Using the Intrinsic Chirality of a Molecule as a Label-Free
Probe to Detect Molecular Adsorption to a Surface by Second Harmonic Generation”, Appl. Spectrosc., 2005, 59, 746-753.
31) Fitchett, B. D., Rollins, J. B., Conboy, J. C., “1-Alkyl-3-Methylimidazolium Bis(perfluoroalkylsulfonyl)imide Water-Immiscible Ionic Liquids: Electrochemical Properties at Liquid-Liquid Interfaces”, J. Electrochem. Soc., 2005, 152, E251-E258.
32) Liu, J., Conboy, J. C., “1,2-Diacyl-Phosphaditylcholine Flip-Flop Measured Directly by Sum-Frequency Vibrational Spectroscopy”, Biophysical J., 2005, 89, 2522–2532.
33) Liu, J., Conboy, J. C., “Structure of a Gel Phase Lipid Bilayer Prepared by the Langmuir-Blodgett/Langmuir-Shäfer Method Characterized by Sum-Frequency Vibrational Spectroscopy”, Langmuir, 2005, 21, 9091 - 9097.
34) Fitchett, B., Rollins, J. B., Conboy, J. C., “Interfacial Tension and Electrocapillary Measurements of the Room Temperature Ionic Liquid/Aqueous Interface”, Langmuir, 2005, 21, 12179-12186.
35) Conboy, J.C., “Sum-Frequency Vibrational Spectroscopy”, McGraw-Hill, 2006 Yearbook of Science and Technology, McGraw-Hill, New York, 2006
36) Evans-Nguyen, Kenyon M., Fuierer, Ryan R., Fitchett, Brian D., Tolles, Lauren R., Conboy, John C., Schoenfisch, Mark H., “Changes in Adsorbed Fibrinogen upon Conversion to Fibrin.”, Langmuir 2006, 22, 5115-5121.
37) Anglin, T. C., Liu, J., Conboy, J. C., “Facile Lipid Flip-Flop in a Phospholipid Bilayer Induced by Gramicidin A Measured by Sum-Frequency Vibrational Spectroscopy Structure”, Biophysical J., 2007, 9, L01-L03.
38) Rollins, J. B., Fitchett, B., Conboy, J. C., “Structure and Orientation of the Imidazolium Cation at the Room Temperature Ionic Liquid/SiO2 Interface Measured by Sum-Frequency Vibrational Spectroscopy”, J. Phys. Chem. B, 2007, 111, 4990-4999
39) Liu, J., Conboy, J. C., “Asymmetric Distribution of Lipids in a Phase Segregated Phospholipid Bilayer Observed by Sum-Frequency Vibrational Spectroscopy”, J. Phys. Chem. C, 2007, 111, 8988-8999
40) Anglin, T. C, Conboy, J. C., “Lateral Pressure Dependence of the Phospholipid Transmembrane Diffusion Rate in Planar-Supported Lipid Bilayers”, Biophysical J., 2008, ASAP
41) Liu, J., Conboy, J. C., “Phase Segregation in Cholesterol + DSPC Lipid Bilayers Examined by Sum-Frequency Vibrational Spectroscopy”, Vibrational Spectroscopy,  2008, (submitted)
42) Smith, K, Gale, B. K., Conboy, J. C., “Micropatterned Lipid Bilayer Arrays Created by a Continuous Flow Micro-spotter”, Langmuir, 2008, (submitted)

Patents:

1) “Stabilized, Biocompatible Supported Lipid Membrane”, Saavedra, S. S., O’Brien, D. F., Kuesters, E. H., Ross, R. E., Bondurant, B., Conboy, J.C., Patent No.: WO2002071944, Date: 3/11/02.

Invited Seminars and Presentations (in chronological order):

1) “From Biocompatible Molecular Structures to Protein Receptor Interactions: Utilizing Polymerized Lipid Platforms for Targeted HIV-1 Inhibition”; Brigham Young University, 9/19/00

2) “Unraveling the Structure of Surface Confined Proteins by Nonlinear Spectroscopy”; Federation of Analytical Chemistry and Spectroscopy Societies National Meeting, Detroit, MI, 10/8/01

3) “Chirality as a Surface Analytical Tool: Measuring Biomolecule Adsorption to Surfaces”, Department of Chemistry, Clarkson University, Potsdam NY, 4/28/03

4) “Are Water-Immiscible Room Temperature Ionic Liquids Really Water Immiscible? Water and Its Effect on the Physical Properties of 1-Alkyl-3-Methylimidazolium Bis(perfluoroalkylsulfonyl) imide Ionic Liquids”, Department of Chemistry, University of Missouri-Columbia, 10/10/03

5) “Membrane Lipid Flip-Flop and More: The Structural and Thermodynamic Properties of Supported Lipid Membranes Measured by Sum-Frequency Vibrational Spectroscopy”, 227th American Chemical Society National Meeting, Anaheim, CA, 3/31/04

6) “Structural and Thermodynamic Measurements of Planar Supported Lipid Bilayers by Sum Frequency Vibrational Spectroscopy”, Northwest Regional American Chemical Society Meeting, Ogden, Utah, 6/6/04

7) “Direct Measurement of Lipid Flip-Flop in Phospholipid Bilayers: Using Sum-Frequency Vibrational Spectroscopy to Measure Membrane Asymmetry”, Department of Chemistry, University of Arizona, 1/27/05

8) “Direct Measurement of Lipid Flip-Flop in Phospholipid Bilayers: Using Sum-Frequency Vibrational Spectroscopy to Measure Membrane Asymmetry”, Department of Chemistry, Purdue University, 2/01/05

9) “Direct Measurement of Lipid Flip-Flop in Phospholipid Bilayers: Using Sum-Frequency Vibrational Spectroscopy to Measure Membrane Asymmetry”, Department of Chemistry and Biochemistry, University of Colorado, 2/21/05

10) “Direct Measurement of Lipid Flip-Flop in Phospholipid Bilayers: Using Sum-Frequency Vibrational Spectroscopy to Measure Membrane Asymmetry”, Department of Chemistry, Colorado State University, 2/23/05

11) “Lipid Transbilayer Transport Measured Directly by Sum-Frequency Vibrational Spectroscopy”, 56th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, Orlando, Fl, 3/3/05

12) “A New Analytical Approach to Measuring Lipid Flip-Flop in Phospholipid Bilayers: Direct Measurement of Membrane Asymmetry Using Sum-Frequency Vibrational Spectroscopy”, 229th American Chemical Society National Meeting, San Diego, CA, 3/14/05, The Next Generation of Analytical Chemistry Professionals

13) “Detecting Molecular Adsorption to a Surface: Using Chirality as a Label-Free Probe”, 229th American Chemical Society National Meeting, San Diego, CA, 3/14/05

14) “Direct Measurement of Lipid Flip-Flop in Phospholipid Bilayers: Using Sum-Frequency Vibrational Spectroscopy to Measure Membrane Asymmetry”, Department of Chemistry, Ohio State University, 3/28/05

15) “Direct Measurement of Lipid Flip-Flop in Phospholipid Bilayers: Using Sum-Frequency Vibrational Spectroscopy to Measure Membrane Asymmetry”, Department of Chemistry, University of California, Davis, 4/5/05

16) “A New Approach to Measuring Lipid Flip-Flop in Phospholipid Bilayers: Direct Measurement of Membrane Asymmetry Using Sum-Frequency Vibrational Spectroscopy”, Department of Chemistry, University of North Carolina, Chapel Hill, 4/18/05

17) “A Novel Label-Free Method to Detect Protein Adsorption to Ligand Arrays Using Second Harmonic Generation Microscopy”, GlaxoSmithKline, 4/19/05

18) “Chiral Imaging: A New Approach to Measuring Protein Adsorption to Patterned Arrays”, Federation of Analytical Chemistry and Spectroscopy Societies National Meeting, 2005, 10/6/05

19) “Using Lasers to Probe the Dynamics of Lipid Membranes”, Department of Chemistry, John Carroll University, 10/26/05

20) “Lipid Flip-Flop in Phospholipid Bilayers: New Insights into Membrane Dynamics”, Department of Chemistry, Case Western Reserve University, 10/27/05

21) “Lipid Flip-Flop in Biological Membranes: What a New Technique Can Tell Us about an Old Problem”, Department of Chemistry Willamette University, Salem OR, 11/08/05

22) “Using Lasers to Probe the Dynamics of Lipid Membranes”, Department of Chemistry, Lewis and Clark College, 11/10/05

23) “Cholesterol and Its Effect on Membrane Dynamics and Structure Studied by Sum-Frequency Vibrational Spectroscopy”, Department of Chemistry, Michigan State University, 12/6/05

24) "Measuring Phospholipid Dynamics in Biological Membranes Using Sum-Frequency Vibrational Spectroscopy", 57th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, Orlando, Florida, 4/12/06

25) “Nonlinear Optical Studies of Interfaces”, 231th American Chemical Society National Meeting, Atlanta, GA, 4/26/06

26) "Physical properties of the room temperature ionic liquid / aqueous interface", 232nd American Chemical Society National Meeting, San Francisco, CA, 9/13/06

27) "Investigating phospholipid bilayer structure and dynamics with sum-frequency vibrational spectroscopy", 232nd American Chemical Society National Meeting, San Francisco, CA, 9/11/06

28) “Peptide and Small Molecule Perturbations of Lipid Structure and Studied by Sum-Frequency Vibrational Spectroscopy”, 58th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, Chicago, Illinois, 2/26/07

29) “Small molecule and peptide perturbations of phospholipid bilayer structure and dynamics”, 233rd American Chemical Society National Meeting, Chicago, IL, 3/27/07

30) “Electrochemical and spectroscopic investigation of the room temperature ionic liquid/aqueous interface”, 233rd American Chemical Society National Meeting, Chicago, IL, 3/28/07

31) "Eukaryotic membrane lipid asymmetry: what a new analytical technique can tell us about an old problem.", Indiana University, Bloomington, IN, 3/25/08

32) Telluride Science Research Center Conference: Nonlinear Optics at Interfaces, Telluirde, CO, 6/23/08

33) “Elucidating the structure of the room temperature ionic liquid/SiO2 interface with sum frequency vibrational spectroscopy”, 236th American Chemical Society National Meeting, Philadelphia, PA, 8/08

34) Craver Award Presentation, Federation of Analytical Chemistry and Spectroscopy Societies National Meeting, Reno, NV, 10/08