Publications

Bagnato, J. D.; Eilers, A. L.; Horton, R. A.; Grissom, C. B. "Synthesis and Characterization of a Cobalamin-Colchicine Conjugates as a Novel Tumor-Targeted Cytotoxin." JOC 2004, 69, 8987-8996.

Horton, R. A.; Bagnato, J. D.; Grissom, C. B. "Structural Determination of 5'-OH Ribofuranoside Modified Cobalamins via 13C and DEPT NMR." JOC 2003, 68, 7108-7111.

Anderson, M. A.; Xu, Y.; Grissom, C. B. "Electron Spin Catalysis by Xenon in an Enzyme." J. Am. Chem. Soc. 2001, 123, 6720-21.
Smeltzer, C. C.; Cannon, M. J.; Pinson, P. R.; Munger, Jr, J. D. ; West, F. G.; Grissom, C. B. "Synthesis and Characterization of Fluorescent Cobalamin (CobalaFluor) Derivatives for Imaging." Org. Lett. 2001, 3, 799-801.

Cannon, M. J., McGreevy, J. M., Holden, J. A.; West, F. G., Grissom, C. B. "The Uptake and Distribution of Fluorescently Labeled Cobalamin in Neoplastic and Healthy Breast Tissue", In Progress in Biomedical Optics and Imaging: Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems X, Proceedings of SPIE, 2000, 3907, 612-615.

Grissom, C.B. "Magnetic Field Dependence of Cobalamin Photochemistry and Enzymes." In B-12, Banerjee, R., Ed., Wiley: New York, 261-270, 1999.

Hogenkamp, H. P. C.; Collins, D. A., West, F. G., Grissom, C. B. "The Pharmacological Uses of Cobalamin Bioconjugates." In B-12, Banerjee, R., Ed., Wiley: New York, 385-410, 1999.

Xu, Y.; Grissom, C. B. "The Chemistry and Enzymology of Cobalamin-Dependent Enzymes." In Comprehensive Natural Products Chemistry, Poulter, C. D., Ed., Elsevier: Oxford, 263-278, 1999.

Mitchell, A. M., Bayomi, A., Natarajan, E., Barrows, L. R., West, F. G., and Grissom, C. B. "Targeting Leukemia Cells with Cobalamin Bioconjugates" In Enzymatic Mechanisms, Frey, P. A.; Northrop, D. B., Eds., 150-154, 1999.

Natarajan, E.; Grissom, C.B. "Insight into the Mechanism of B-12 Dependent Enzymes: Magnetic Field Effects as a Probe of Reaction Mechanism and the Role of the Ribofuranose Ring Oxygen." in Vitamin B12 and B12 Proteins, Krautler, B.; Arigoni, D; Golding, B., eds, Wiley-VCH: Weinheim, 1998.

Howard, W. A.; Bayomi, A.; Natarajan, E.; Aziza, M. A.; El-Ahmady, O.; Grissom, C. B.; West, F. G. "Sonolysis Promotes Indirect Co-C Bond Cleavage of Alkylcob(III)alamin Bioconjugates." Bioconj. Chem. 1997, 8, 498-502.

Taraban, M.B.; Leshina, T.V.; Anderson, M.A.; Grissom, C.B. "Magnetic Field Dependence and the Role of Electron Spin in Heme Enzymes: Horseradish Peroxidase." J. Am. Chem. Soc. 1997, 119, 5768-5769.

Taoka, S.; Padmakumar, R.; Grissom, C.B.; Banerjee, R. "Magnetic Field Effects on Coenzyme B-12 Dependent Enzymes: Validation of Ethanolamine Ammonia Lyase Results and Extension to Human Methylmalonyl CoA Mutase." Bioelectromagnetics 1997, 18, 506-513.

Natarajan, E.; Grissom, C.B. "Use of Magnetic Field Effects to Study Coenzyme B-12 Dependent Reactions." Meth. Enzymol. 1997, 281, 235-247.

Kruppa, A.I.; Taraban, M.B.; Leshina, T.V.; Natarajan, E.; Grissom, C.B. "CIDNP in the Photolysis of Coenzyme B-12 Model Compounds Suggests C-Co Bond Homolysis Occurs from the Singlet State." Inorg. Chem. 1997, 36, 758-759.

Anderson, M.A.; Grissom, C.B. "Increasing the Heavy Atom Effect of Xenon by Adsorption to Zeolites: Photolysis of 2,3-Diazabicyclo- [2.2.2]oct-2-ene." J. Am. Chem. Soc. 1996, 118, 9552-9556.

Natarajan, E.; Grissom, C.B. "Origin of Magnetic Field Dependent Recombination in Alkylcobalamin Radical Pairs." Photochem. Photobiol. 1996, 64, 286-295.

Hwang, C.-C.; Grissom, C.B. "Large Deuterium Kinetic Isotope Effects in Soybean Lipoxygenase." Am. Oil Chemists Assoc. monograph, pp 116-137, 1996.

Lott, W.B.; Chagovetz, A.M.; Grissom, C.B. "Alkyl Radical Geometry Controls Geminate Cage Recombination in Alkylcobalamins." J. Am. Chem. Soc. 1995, 117, 12194-12201.

Miller, J.R.; Edmondson, D.E.; Grissom, C.B. "Mechanistic Probes of Monoamine Oxidase B Catalysis: Rapid-Scan Stopped Flow and Magnetic Field Independence of the Reductive Half-Reaction." J. Am. Chem. Soc. 1995, 117, 7830-7831.

Anderson, M.A.; Grissom, C.B. "Photolysis of 2,3 Diazabicyclo[2.2.2]- oct-2-ene (DBO): Electronic Spin Determines the Distribution of Products." J. Am. Chem. Soc. 1995, 117, 5041-5048.

Harkins, T.T.; Grissom, C.B. "The Magnetic Field Dependent Step in B-12 Ethanolamine Ammonia Lyase is Radical-Pair Recombination." J. Am. Chem. Soc. 1995, 117, 566-568.

Grissom, C.B. "Magnetic Field Effects in Biology: A Survey of Possible Mechanisms with Emphasis on Radical-Pair Recombination." Chem. Rev. 1995, 95, 3-24.

Lott, W.B.; Evans, T.J.; Grissom, C.B. "Absence of Intersystem Crossing in 1,4-Didehydrobenzene." Perkin Trans. 2, 1994, 2583-2586.

Benson, D.; Mohammad, S.F.; Grissom, C.B.; Burns, G.L. "Magnetic Field Enhancement of Antibiotic Activity in Biofilm-Forming Pseudomonas aeruginosa." Journal of the American Society of Artificial and Internal Organs, 1994, 40, 371-376.

Harkins, T.T.; Grissom, C.B. "Magnetic Field Effects on B-12 Ethanolamine Ammonia Lyase: Evidence for a Radical Mechanism." Science 1994, 263, 958-960.

Hwang, C.-C., Grissom, C.B. "Unusually Large Deuterium Isotope Effects in Soybean Lipoxygenase are Not Caused by a Magnetic Isotope Effect." J. Am. Chem. Soc. 1994, 116, 795-796.

Chagovetz, A.M.; Grissom, C.B. "Magnetic Field Effects in Adenosylcob-(III)alamin Photolysis: Relevance to B12 Enzymes." J. Am. Chem. Soc. 1993, 115, 12152-12157.

Grissom, C.B.; Chagovetz, A.M. "Magnetic Field Effects in Model B-12 Enzymatic Reactions: The Photolysis of Methylcob(III)alamin." Zeitschrift fur Physikalische Chemie 1993, 182, 181-188.

Grissom, C.B.; Wang, Z.; Chagovetz, A.M. "Use of Viscosigens to Stabilize Vitamin B-12 Solutions Against Photolysis." J. Pharmaceutical Sciences 1993, 82, 641-643.

Bartlett, P.A.; McLaren, K.L.; Alberg, D.G.; Fassler, A.; Nyfeler, R.; Lauhon, C.T.; Grissom, C.B. "Exploration of the Shikimic Acid Pathway: Opportunities for the Study of Enzyme Mechanisms Through the Synthesis of Intermediates and Inhibitors", in Prospects for Amino Acid Biosynthesis Inhibitors in Crop Protection and Pharmaceutical Chemistry, L.G. Copping, Ed.; Society of Chemical Industry, 155-170, 1989.

Grissom, C.B.; Markley, J.L. "Staphylococcal Nuclease Active Site Amino Acids: The pH Dependence of Tyrosines and Arginines by 13C NMR and a Correlation with Kinetic Studies." Biochemistry 1989, 28, 2116-2124.

Grissom, C.B.; Cleland, W.W. "Isotope Effect Studies of the Chemical Mechanism of Pig Heart NADP Isocitrate Dehydrogenase." Biochemistry 1988, 27, 2934-2943.

Grissom, C.B.; Cleland, W.W. "Isotope Effect Studies of Chicken Liver NADP Malic Enzyme: The Role of the Metal Ion and Viscosity Dependence." Biochemistry 1988, 27, 2927-2934.

Grissom, C.B.; Cleland, W.W. "2-Keto-3-fluoroglutarate: A Useful Mechanistic Probe of 2-Ketoglutarate-Dependent Enzyme Systems." Biochem. Biophys. Acta 1988, 916, 437-445.

Grissom, C.B.; Willeford, K.O.; Wedding, R.T. "Isotope Effect Studies of the Chemical Mechanism of NAD Malic Enzyme from Crassula." Biochemistry 1987, 26, 2594-2596.

Grissom, C.B.; Cleland, W.W. "Carbon Isotope Effects on the Metal Ion Catalyzed Decarboxylation of Oxalacetate." J. Am. Chem. Soc. 1986, 108, 5582-5583.

Grissom, C.B.; Cleland, W.W. "The use of Intermediate Partitioning to Calculate Intrinsic Isotope Effects for the Reaction Catalyzed by Malic Enzyme." Biochemistry 1985, 24, 944-948.

Canellas, P.F.; Grissom, C.B.; and Wedding, R.T. "Allosteric Regulation of the NAD Malic Enzyme from Cauliflower: Activation by Sulfate." Arch. Biochem. Biophys. 1983, 220, 116-132.

Grissom, C.B.; Canellas, P.F.; and Wedding, R.T. "Allosteric Regulation of the NAD Malic Enzyme from Cauliflower: Activation by Fumarate and Coenzyme A." Arch. Biochem. Biophys. 1983, 220, 133-144.

Publications

Bagnato, J. D.; Eilers, A. L.; Horton, R. A.; Grissom, C. B. "Synthesis and Characterization of a Cobalamin-Colchicine Conjugates as a Novel Tumor-Targeted Cytotoxin." JOC 2004, 69, 8987-8996. Horton, R. A.; Bagnato, J. D.; Grissom, C. B. "Structural Determination of 5'-OH Ribofuranoside Modified Cobalamins via 13C and DEPT NMR." JOC 2003, 68, 7108-7111. Anderson, M. A.; Xu, Y.; Grissom, C. B. "Electron Spin Catalysis by Xenon in an Enzyme." J. Am. Chem. Soc. 2001, 123, 6720-21. Smeltzer, C. C.; Cannon, M. J.; Pinson, P. R.; Munger, Jr, J. D. ; West, F. G.; Grissom, C. B. "Synthesis and Characterization of Fluorescent Cobalamin (CobalaFluor) Derivatives for Imaging." Org. Lett. 2001, 3, 799-801. Cannon, M. J., McGreevy, J. M., Holden, J. A.; West, F. G., Grissom, C. B. "The Uptake and Distribution of Fluorescently Labeled Cobalamin in Neoplastic and Healthy Breast Tissue", In Progress in Biomedical Optics and Imaging: Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems X, Proceedings of SPIE, 2000, 3907, 612-615. Grissom, C.B. "Magnetic Field Dependence of Cobalamin Photochemistry and Enzymes." In B-12, Banerjee, R., Ed., Wiley: New York, 261-270, 1999. Hogenkamp, H. P. C.; Collins, D. A., West, F. G., Grissom, C. B. "The Pharmacological Uses of Cobalamin Bioconjugates." In B-12, Banerjee, R., Ed., Wiley: New York, 385-410, 1999. Xu, Y.; Grissom, C. B. "The Chemistry and Enzymology of Cobalamin-Dependent Enzymes." In Comprehensive Natural Products Chemistry, Poulter, C. D., Ed., Elsevier: Oxford, 263-278, 1999. Mitchell, A. M., Bayomi, A., Natarajan, E., Barrows, L. R., West, F. G., and Grissom, C. B. "Targeting Leukemia Cells with Cobalamin Bioconjugates" In Enzymatic Mechanisms, Frey, P. A.; Northrop, D. B., Eds., 150-154, 1999. Natarajan, E.; Grissom, C.B. "Insight into the Mechanism of B-12 Dependent Enzymes: Magnetic Field Effects as a Probe of Reaction Mechanism and the Role of the Ribofuranose Ring Oxygen." in Vitamin B12 and B12 Proteins, Krautler, B.; Arigoni, D; Golding, B., eds, Wiley-VCH: Weinheim, 1998. Howard, W. A.; Bayomi, A.; Natarajan, E.; Aziza, M. A.; El-Ahmady, O.; Grissom, C. B.; West, F. G. "Sonolysis Promotes Indirect Co-C Bond Cleavage of Alkylcob(III)alamin Bioconjugates." Bioconj. Chem. 1997, 8, 498-502. Taraban, M.B.; Leshina, T.V.; Anderson, M.A.; Grissom, C.B. "Magnetic Field Dependence and the Role of Electron Spin in Heme Enzymes: Horseradish Peroxidase." J. Am. Chem. Soc. 1997, 119, 5768-5769. Taoka, S.; Padmakumar, R.; Grissom, C.B.; Banerjee, R. "Magnetic Field Effects on Coenzyme B-12 Dependent Enzymes: Validation of Ethanolamine Ammonia Lyase Results and Extension to Human Methylmalonyl CoA Mutase." Bioelectromagnetics 1997, 18, 506-513. Natarajan, E.; Grissom, C.B. "Use of Magnetic Field Effects to Study Coenzyme B-12 Dependent Reactions." Meth. Enzymol. 1997, 281, 235-247. Kruppa, A.I.; Taraban, M.B.; Leshina, T.V.; Natarajan, E.; Grissom, C.B. "CIDNP in the Photolysis of Coenzyme B-12 Model Compounds Suggests C-Co Bond Homolysis Occurs from the Singlet State." Inorg. Chem. 1997, 36, 758-759. Anderson, M.A.; Grissom, C.B. "Increasing the Heavy Atom Effect of Xenon by Adsorption to Zeolites: Photolysis of 2,3-Diazabicyclo- [2.2.2]oct-2-ene." J. Am. Chem. Soc. 1996, 118, 9552-9556. Natarajan, E.; Grissom, C.B. "Origin of Magnetic Field Dependent Recombination in Alkylcobalamin Radical Pairs." Photochem. Photobiol. 1996, 64, 286-295. Hwang, C.-C.; Grissom, C.B. "Large Deuterium Kinetic Isotope Effects in Soybean Lipoxygenase." Am. Oil Chemists Assoc. monograph, pp 116-137, 1996. Lott, W.B.; Chagovetz, A.M.; Grissom, C.B. "Alkyl Radical Geometry Controls Geminate Cage Recombination in Alkylcobalamins." J. Am. Chem. Soc. 1995, 117, 12194-12201. Miller, J.R.; Edmondson, D.E.; Grissom, C.B. "Mechanistic Probes of Monoamine Oxidase B Catalysis: Rapid-Scan Stopped Flow and Magnetic Field Independence of the Reductive Half-Reaction." J. Am. Chem. Soc. 1995, 117, 7830-7831. Anderson, M.A.; Grissom, C.B. "Photolysis of 2,3 Diazabicyclo[2.2.2]- oct-2-ene (DBO): Electronic Spin Determines the Distribution of Products." J. Am. Chem. Soc. 1995, 117, 5041-5048. Harkins, T.T.; Grissom, C.B. "The Magnetic Field Dependent Step in B-12 Ethanolamine Ammonia Lyase is Radical-Pair Recombination." J. Am. Chem. Soc. 1995, 117, 566-568. Grissom, C.B. "Magnetic Field Effects in Biology: A Survey of Possible Mechanisms with Emphasis on Radical-Pair Recombination." Chem. Rev. 1995, 95, 3-24. Lott, W.B.; Evans, T.J.; Grissom, C.B. "Absence of Intersystem Crossing in 1,4-Didehydrobenzene." Perkin Trans. 2, 1994, 2583-2586. Benson, D.; Mohammad, S.F.; Grissom, C.B.; Burns, G.L. "Magnetic Field Enhancement of Antibiotic Activity in Biofilm-Forming Pseudomonas aeruginosa." Journal of the American Society of Artificial and Internal Organs, 1994, 40, 371-376. Harkins, T.T.; Grissom, C.B. "Magnetic Field Effects on B-12 Ethanolamine Ammonia Lyase: Evidence for a Radical Mechanism." Science 1994, 263, 958-960. Hwang, C.-C., Grissom, C.B. "Unusually Large Deuterium Isotope Effects in Soybean Lipoxygenase are Not Caused by a Magnetic Isotope Effect." J. Am. Chem. Soc. 1994, 116, 795-796. Chagovetz, A.M.; Grissom, C.B. "Magnetic Field Effects in Adenosylcob-(III)alamin Photolysis: Relevance to B12 Enzymes." J. Am. Chem. Soc. 1993, 115, 12152-12157. Grissom, C.B.; Chagovetz, A.M. "Magnetic Field Effects in Model B-12 Enzymatic Reactions: The Photolysis of Methylcob(III)alamin." Zeitschrift fur Physikalische Chemie 1993, 182, 181-188. Grissom, C.B.; Wang, Z.; Chagovetz, A.M. "Use of Viscosigens to Stabilize Vitamin B-12 Solutions Against Photolysis." J. Pharmaceutical Sciences 1993, 82, 641-643. Bartlett, P.A.; McLaren, K.L.; Alberg, D.G.; Fassler, A.; Nyfeler, R.; Lauhon, C.T.; Grissom, C.B. "Exploration of the Shikimic Acid Pathway: Opportunities for the Study of Enzyme Mechanisms Through the Synthesis of Intermediates and Inhibitors", in Prospects for Amino Acid Biosynthesis Inhibitors in Crop Protection and Pharmaceutical Chemistry, L.G. Copping, Ed.; Society of Chemical Industry, 155-170, 1989. Grissom, C.B.; Markley, J.L. "Staphylococcal Nuclease Active Site Amino Acids: The pH Dependence of Tyrosines and Arginines by 13C NMR and a Correlation with Kinetic Studies." Biochemistry 1989, 28, 2116-2124. Grissom, C.B.; Cleland, W.W. "Isotope Effect Studies of the Chemical Mechanism of Pig Heart NADP Isocitrate Dehydrogenase." Biochemistry 1988, 27, 2934-2943. Grissom, C.B.; Cleland, W.W. "Isotope Effect Studies of Chicken Liver NADP Malic Enzyme: The Role of the Metal Ion and Viscosity Dependence." Biochemistry 1988, 27, 2927-2934. Grissom, C.B.; Cleland, W.W. "2-Keto-3-fluoroglutarate: A Useful Mechanistic Probe of 2-Ketoglutarate-Dependent Enzyme Systems." Biochem. Biophys. Acta 1988, 916, 437-445. Grissom, C.B.; Willeford, K.O.; Wedding, R.T. "Isotope Effect Studies of the Chemical Mechanism of NAD Malic Enzyme from Crassula." Biochemistry 1987, 26, 2594-2596. Grissom, C.B.; Cleland, W.W. "Carbon Isotope Effects on the Metal Ion Catalyzed Decarboxylation of Oxalacetate." J. Am. Chem. Soc. 1986, 108, 5582-5583. Grissom, C.B.; Cleland, W.W. "The use of Intermediate Partitioning to Calculate Intrinsic Isotope Effects for the Reaction Catalyzed by Malic Enzyme." Biochemistry 1985, 24, 944-948. Canellas, P.F.; Grissom, C.B.; and Wedding, R.T. "Allosteric Regulation of the NAD Malic Enzyme from Cauliflower: Activation by Sulfate." Arch. Biochem. Biophys. 1983, 220, 116-132. Grissom, C.B.; Canellas, P.F.; and Wedding, R.T. "Allosteric Regulation of the NAD Malic Enzyme from Cauliflower: Activation by Fumarate and Coenzyme A." Arch. Biochem. Biophys. 1983, 220, 133-144.