Publications
99. "Synthetic Studies Toward the Bryostatins. A Substrate Controlled Approach to the A-Ring" Gary E. Keck, Dennie S. Welch, and Paige K. Vivian, Org. Lett. 2006, in press.
98. "Total Synthesis of (+) Dactylolide" Carina C. Sanchez and Gary E. Keck, Org. Lett. 2005, 7, 3053-3056.
97. "Synthetic Studies on the Bryostatins: Synthetic Routes to Analogues Containing the Tricyclic Macrolactone Core" Gary E. Keck and Anh P. Truong, Org. Lett. 2005, 7, 2153-2156.
96. "Synthetic Studies on the Bryostatins: Preparation of a Truncated BC-Ring Intermediate by Pyran Annulation" Gary E. Keck and Anh P. Truong, Org. Lett. 2005, 7, 2149-2152.
95. "Stereoselective Synthesis of the C1-C13 Subunit of Dolabelide B" Gary E. Keck and Mark D. McLaws, Tetrahedron Lett. 2005, 46, 4911-4914.
94. "Enantio- and Diastereoselective Additions to Aldehydes Using the Bifunctional Reagent 2-(Chloromethyl)-3-(tributylstannyl)propene: Application to a Synthesis of the C16-C27 segment of Bryostatin" Gary E. Keck, Tao Yu, and Mark D. McLaws, J. Org. Chem. 2005, 70, 2543-2550.
93. "Intramolecular Baylis-Hillman and Morita Reactions Using Unsaturated Thiol Ester Substrates Containing Enolizable Aldehydes", Gary E. Keck and Dennie P. Welch, Org. Lett. 2002, 4, 3687-3690.
92. "Directed Reduction of b-Amino Ketones to Syn or Anti 1,3-Amino Alcohol Derivatives", Gary E. Keck and Anh P. Truong, Org. Lett. 2002, 4, 3131-3134.
91. "Pyran Annulation: Asymmetric Synthesis of 2,6-Disubstituted-4-methylene Tetrahydropyrans", Gary E. Keck, Jonathan A. Covel, Tobias Schiff, and Tao Yu, Org. Lett. 2002, 4, 1189-1192.
90. "Total Synthesis of the Immunosuppressant
(-)-Pironetin (PA48153C) ", Gary E. Keck,
89. "Asymmetric Total Synthesis of Rhizoxin D”, Gary E. Keck, Carrie A. Wager, Travis T. Wager, Kenneth A. Savin, Jonathan A. Covel, Mark D. McLaws, Dhileep Krishnamurthy, and Victor J. Cee, Angew. Chem. Int. Ed. (English) 2001, 40, 231-234.
88. "A Direct and Mild Conversion of Tertiary Aryl Amides to Methyl Esters Using Trimethyloxonium Tetrafluoroborate: A Very Useful Complement to Directed Metalation Reactions", Gary E. Keck, Mark D. McLaws, and Travis T. Wager, Tetrahedron 2000, 56, 9875-9883.
87. "Macrolactonization of Hydroxy Acids Using a Polymer-bound Carbodiimide", Gary E. Keck, Carina Sanchez, and Carrie A. Wager, Tetrahedron Lett. 2000, 41, 8673-8676.
86. "The First Directed Reduction of b-Alkoxy Ketones to Anti-1,3-Diol Monoethers: Identification of Spectator and Director Alkoxy Groups", Gary E. Keck and Carrie A. Wager, Org. Lett. 2000, 2, 2307-2309.
85. "Generation and Reactivity of Oxazolidinone-Derived N-Acyl Radicals", Gary E. Keck and Mark C. Grier, Synlett 1999, 1657-1659.
84. "A Versatile
Preparation of a-b Unsaturated Lactones from Homoallylic Alcohols",
Gary E. Keck, Xiang-Yi Li and
83. "Reductive Cleavage of N-O Bonds in Hydroxylamines and Hydroxamic Acid Derivatives Using Samarium Diiodide", Gary E. Keck, Travis T. Wager and Stanton F. McHardy, Tetrahedron 1999, 55, 11755-11772.
82. "Catalytic Asymmetric Allylation Reactions Using BITIP Catalysis and 2-Substituted Allylstannanes as Surrogates for b-Keto Ester Dianions", Gary E. Keck and Tao Yu, Org. Lett. 1999, 2, 289-292.
81. "Total Syntheses of (-)-Lycoricidine, (+)-Lycoricidine, and (+)-Narciclasine via 6-exo Cyclizations of Substituted Vinyl Radicals with Oxime Ethers", Gary E. Keck, Travis T. Wager, and J. F. D. Rodriquez, J. Am. Chem. Soc. 1999, 121, 5176-5190.
80. "Synthetic Studies Toward the Total Synthesis of Swinholide A. 1. Stereoselective Construction of the C19-C32 Subunit", Gary E. Keck and Gregory D. Lundquist, J. Org. Chem. 1999, 64, 4482-4491.
79. "Diastereoselective 6-exo Radical Cyclizations to Oxime Ethers: Total Synthesis of 7-Deoxypancratistatin", Gary E. Keck, Stanton F. McHardy and Jerry A. Murry, J. Org. Chem. 1999, 64, 4465-4476.
78. "An Especially Convenient Stereoselective Reduction of b-Hydroxy Ketones to Anti 1,3 Diols Using Samarium Diiodide", Gary E. Keck, Carrie A. Wager, Thorsten Sell and Travis T. Wager, J. Org. Chem. 1999, 64, 2172-2173.
77. "A Second-Generation Radical-Based Synthesis of (+)-7-Deoxypancratistatin", Gary E. Keck, Travis T. Wager, and Stanton. F. McHardy, J. Org. Chem. 1998, 63, 9164-9165.
76. "Catalytic Asymmetric Allylation (CAA) Reactions: (S)-1-(Phenylmethoxy)-4-Penten-2-ol", Gary E. Keck and Dhileep Krishnamurthy, Org. Syn. 1998, 75, 12-18.
75. "Total Synthesis of ent-Lycoricidine via a Thiyl Radical Addition - Cyclization Sequence”, Gary E. Keck and Travis T. Wager, J. Org. Chem. 1996, 61, 8366-8367.
74. "A Convenient Preparation of Chiral Primary Alcohols via Catalytic Asymmetric Reduction of Aldehydes Using Bu3SnD", Gary E. Keck and Dhileep Krishnamurthy, J. Org. Chem. 1996, 61, 7638-7639.
73. "Synthetic Studies on the Rhizoxins. II. An Approach to the C10-C26 Subunit Using "Substrate Directed" Allylstannane Additions to Aldehydes", Gary E. Keck, Kenneth A. Savin, Michael A. Weglarz, and Erik N. K. Cressman, Tetrahedron Lett. 1996, 37, 3291-3294.
72. "A Simple and Practical Synthesis of (+)-2-Bromobicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde via Chiral Lewis Acid Catalyzed [4+2] Cycloaddition" Gary E. Keck and Dhileep Krishnamurthy, Synthetic Communications 1996, 26, 367.
71. "Reductive Cleavage of N-O Bonds in Hydroxylamine and Hydroxamic Acid Derivatives Using SmI2/THF", Gary E. Keck, Stanton F. McHardy, and Travis T. Wager, Tetrahedron Lett. 1995, 36, 7419.
70. "Catalytic Enantioselective Synthesis of Dihydropyrones via Formal Hetero Diels-Alder Reactions of "Danishefsky's Diene" with Aldehydes" Gary E. Keck, , Xiang-Yi. Li, and Dhileep Krishnamurthy, J. Org. Chem. 1995, 60, 5998-5999.
69. "Total Synthesis of (+)-7-deoxypancratistatin." Gary E. Keck, Stanton F. McHardy, and Jerry A. Murry, J. Am. Chem. Soc. 1995, 117, 7289.
68. "Pronounced Solvent and Concentration Effects in an Enantioselective Mukaiyama Aldol Condensation Using BINOL-Titanium (IV) Catalysts." Gary E. Keck and Dhileep Krishnamurthy, J. Am. Chem. Soc. 1995, 117, 2363-2364.
67. "Use of Samarium Diiodide as an Alternative to Sodium/Mercury Amalgam in the Julia-Lythgoe Olefination." Gary E. Keck, Kenneth A. Savin, and Michael A. Weglarz, J. Org. Chem. 1995, 60, 3194-3204.
66. "Intramolecular Allylstannane-Aldehyde Cyclizations: Stereochemical Results with Flexible Tethers for Reactions Forming Vinylcyclohexanols." Gary E. Keck, Shawn M. Dougherty, and Kenneth A. Savin, J. Am. Chem. Soc. 1995, 117, 6210.
65. "Effects of Olefin Geometry on the Stereochemistry of Lewis Acid Mediated Additions of Crotylstannanes to Aldehydes." Gary E. Keck, Kenneth A. Savin, Erik N. K. Cressman, and Duain E. Abbott, J. Org. Chem. 1994, 59, 7889.
64. "Asymmetric Synthesis of Homopropargylic Alcohols From Aldehydes and Allenyltri-n-butylstannane." Gary E. Keck, Dhileep Krishnamurthy, and Xi. Chen, Tetrahedron Lett. 1994, 35, 8323.
63. "Total Synthesis of (+)-Carbonolide B." Gary E. Keck, Anandan Palani, and Stanton F. McHardy, J. Org. Chem. 1994, 59, 3113.
62. "An Acylnitroso Cycloaddition Approach to the Synthesis of Highly Oxygenated Indolizidine Alkaloids." Gary E. Keck and Duane R. Romer, J. Org. Chem. 1993, 22, 6083.
61. "A Three Component Free Radical Coupling Reaction: Vicinal Dialkylation of a.b-Unsaturated Ketones and Esters." Gary E. Keck and Cheryl P. Kordik, Tetrahedron Lett. 1993, 34, 6875.
60. "Catalytic Asymmetric Allylation (CAA) Reactions. 3. Extension to Methallylstannane, Comparison of Procedures, and Observation of a Non-Linear Effect." Gary E. Keck, Dhileep Krishnamurthy, and Mark C. Grier, J. Org. Chem. 1993, 58, 6543-6544.
59. "Catalytic Asymmetric Allylation (CAA) Reactions. II. A New Enantioselective Allylation Procedure" Gary E. Keck and Leo S. Geraci, Tetrahedron Lett. 1993, 34, 7827.
58. "Catalytic Asymmetric Allylation of Aldehydes." Gary E. Keck, Kenneth H. Tarbet, and Leo S. Geraci, J. Am. Chem. Soc. 1993, 115, 8467-8468.
57. "Some Unusual Reactions of Weinreb Amides." Gary E. Keck, Stanton F. McHardy, and Jerry A. Murry, Tetrahedron Lett. 1993, 34, 6215.
56. "Intramolecular Allylstannane-Carbonyl Condensations. Formation of Vinylcyclopropane Derivatives and an Unusual Dimeric Product" Gary E. Keck and Shawn D. Tonnies, Tetrahedron Lett. 1993, 34, 4607.
55. "Synthetic Studies on the Rhizoxins. I. Two Stereoselective Routes to a Functionalized C1-C9 Subunit." Gary E. Keck, Min Park, and Dhileep Krishnamurthy, J. Org. Chem. 1993, 58, 3787-3788.
54. "A Conjunctive Approach to the Synthesis of Functionalized Piperidines from Imines." Gary E. Keck and Aanandan Palani, Tetrahedron Lett. 1993, 34, 3223.
53. "Yeast-Mediated Resolution of b-Keto Esters of Prochiral Alcohols." Thomas Hudlicky, T. Tsunoda, K. G. Gadamasetti, Jerry A. Murry, and Gary E. Keck , J. Org. Chem. 1991, 56, 3619.
52. "Total Synthesis of (-)-Colletol." Gary E. Keck and Jerry A. Murry, J. Org. Chem. 1991, 56, 6606-6611.
51. "A Useful New Chiral Synthon From Malic Acid: Chelation Controlled Activation as a Route to Regioselectivity." Gary E. Keck, Merritt B. Andrus, and Duane R. Romer, J. Org. Chem. 1991, 56, 417.
50. "Radical Cyclization Reactions from a-Silyloxy Phenylselenides: an Alternative to Acyl Radicals." Gary E. Keck and Aahmed M. Tafesh, Synlett 1990, 5, 257.
49. "Free Radical Addition-Fragmentation Reactions in Synthesis: A 'Second Generation' Synthesis of (+)-Pseudomonic Acid C." Gary E. Keck and Ahmed M. Tafesh, J. Org. Chem. 1989, 54, 5845.
48. "Intramolecular Allylstannane Cyclizations in Alkaloid Synthesis; Applications to Pyrrolizidine Alkaloids." Gary E. Keck, Erik N. K. Cressman, and Eric J. Enholm, J. Org. Chem. 1989, 54, 4345.
47. "Mechanistic Variability in the Lewis Acid-Promoted Reactions of Aldehydes with Organostannanes", Gary E. Keck, Steven Castellino, and Merritt B. Andrus in Selectivities in Lewis Acid Promoted Reactions; D. Schinzer, Ed.; NATO ASI Series C; Kluwer Academic: Dordrecht, 1989; Vol. 289, Chapter 5.
46. "On the Mechanism of SnCl4 Promoted Additions of Allylstannanes to Aldehydes: A Response to Denmark, Wilson, and Willson" Gary E. Keck, Merritt B. Andrus, and Steven Castellino, J. Am. Chem. Soc. 1989, 111, 8136.
45. "Total Synthesis of (+)-Colletodiol: New Methodology for the Synthesis of Macrolactones", Gary E. Keck, Eugene P. Boden, and Michael R. Wiley, J. Org. Chem. 1989, 54, 896.
44. "A Free Radical Addition-Fragmentation Reaction for the Preparation of Vinyl Sulfones and Phosphine Oxides", Gary E. Keck Jeffrey H. Byers, and Ahmed M. Tafesh, J. Org. Chem. 1988, 53, 1127.
43 "b-Stannylenones as Radical Traps: A Very Direct Route to PGF2a", Gary E. Keck and Duane A. Burnett, J. Org. Chem. 1987, 52, 2958.
42. "Direct Evidence for the Absence of Chelation with b-Silyloxy Aldehydes and Lewis Acids", Gary E. Keck and Steven. Castellino, Tetrahedron Lett. 1987, 28, 281.
41. "The Effect of Protecting Groups on Chelation Control", Scott D. Kahn, Gary E. Keck, and Warren J. Hehre, Tetrahedron Lett. 1987, 28, 279.
40. "New Allylstannanes for the Connective Construction of Monoprotected Vicinal Diols", Gary E. Keck, Duain E. Abbott, and Michael R. Wiley, Tetrahedron Lett. 1987, 28, 139.
39. "Dramatic Effects of Oxygen Substituents on 1,3-Asymmetric Induction in Additions of Allyltriphenylstannane to b-alkoxy Aldehydes: A Chemical and Spectroscopic Investigation", Gary E. Keck, Steven Castellino, and Michael R. Wiley, J. Org. Chem. 1986, 51, 5478.
38. "On the Origins of Diastereofacial Selectivity in "Chelation Controlled" Nucleophilic Additions to b-alkoxy Aldehydes: Solution Structures of Lewis Acid Complexes Via NMR Spectroscopy", Gary E. Keck and Steven Castellino, J. Am. Chem. Soc. 1986 108, 3847.
37. "A Highly Convergent Total Synthesis of (+)-Compactin", Gary E. Keck and David F. Kachensky, J. Org. Chem. 1986, 51, 2487.
36. "A New 'One Electron' Carbon-Carbon Bond Forming Reaction: Separation of the Chain Propagation Steps in Free Radical Allylation", Gary E. Keck and Jeffrey H. Byers, J. Org. Chem. 1985, 50, 5442.
35. "Pseudomonic Acid C from L-Lyxose", Gary E. Keck, David F. Kachensky, and Eric J. Enholm, J. Org. Chem. 1985, 50, 4317.
34. "One Electron C-C Bond Forming Reactions via Allylstannanes: Scope and Limitations", Gary E. Keck, Eric J. Enholm, John B. Yates, and Michael R. Wiley, Tetrahedron Symposium in Print 1985, 41, 4079.
33. "Synthetic Studies
on Pyrrolizidine Alkaloids. II. Intramolecular Addition of Radicals
and Electrophiles to Allylstannanes as Methods for Ring Closure",
32. "Proton-Transfer Steps in Steglich Esterification: A Very Practical New Method for Macrolactonization", Eugene P. Boden and Gary E. Keck, J. Org. Chem. 1985, 50, 2394-2395.
31. "A Useful Wittig Reagent for the Stereoselective Synthesis of trans-a,b Unsaturated Thiol Esters", Gary E. Keck, Eugene P. Boden, and Scott A. Mabury, J. Org. Chem. 1985, 50, 709.
30. "Homoallyl Amines From Aldimines and Allylstannanes", Gary E. Keck and Eric J. Enholm, J. Org. Chem. 1985, 50, 146.
29. "Observations On The Choice of Lewis Acid and Mode of Addition for Lewis Acid Mediated Reaction of Crotyltri-n-butylstannane with Aldehydes: Convenient and Highly Selective Access to Both Erythro and Threo Products", Gary E. Keck, Duain E. Abbott, Eugene P. Boden, and Eric J. Enholm, Tetrahedron Lett. 1984, 25, 3927.
28. "Stereochemical Consequences for the Lewis Acid Mediated Additions of Allyl and Crotyltri-n-butylstannane to Chiral b-Hydroxyaldehyde Derivatives", Gary E. Keck and D. E. Abbott, Tetrahedron Lett. 1984, 25, 1883.
27. "Chelation Controlled Diasterofacial Selectivity in Crotyltri-n-Butylstannane Additions to a-Alkoxyaldehydes," Gary E. Keck and Eugene P. Boden, Tetrahedron Lett. 1984, 25, 1879.
26. "Two New Methods for the Synthesis of C-Glycosides," Gary E. Keck, Eric J. Enholm, and David F. Kachensky, Tetrahedron Lett. 1984, 25, 1867.
25. "Total Synthesis of Pseudomonic Acid C," Gary E. Keck, David F. Kachensky, and Eric J. Enholm, J. Org. Chem. 1984, 49, 1462.
24. "Sterocontrolled Additions of Allyltri-n-butylstannane to a-Hydroxyaldehyde Derivatives: A Useful Route to Monoprotected Erythro or Threo Diols," Gary E. Keck and Eugene P. Boden Tetrahedron Lett. 1984, 25, 265.
23. "Hydrogen Transfer From Crotyltri-n-butylstannane to Carbon Radicals", Gary E. Keck and John B. Yates, J. Organomet. Chem. 1983, 248, C21-C25.
22. "Carbon-Carbon Bond Formation via the Reaction of Trialkylallystannanes with Organic Halides", Gary E. Keck and John B. Yates, J. Am. Chem. Soc. 1982, 104, 5829.
21. "A Versatile Method for the Preparation of Allenic Alcohols", Gary E. Keck and Robert R. Webb, II, Tetrahedron Lett. 1982, 23, 3051.
20. "A Novel Synthesis of (±)-Perhydrohistrionicotoxin," Gary E. Keck and John B. Yates, J. Org. Chem. 1982, 47, 3590.
19. "Alkaloid Synthesis via Intramolecular Ene Reaction. II. Application to d,l- Mesembrine and d,1-dihydro-Maritidine," Gary E. Keck and Robert R. Webb, II, J. Org. Chem. 1982, 47 1302.
18. "Synthetic
Studies on Lycoricidine. II. An
17. "A Versatile Method for Carbon Nitrogen Bond Formation via Ene Reactions of Acylnitroso Compounds," Gary E. Keck, Robert R. Webb II and John. Yates, Tetrahedron Symposium in Print 1981, 37, 4007.
16. "Alkaloid Synthesis via Intramolecular Ene Reactions. I. (±)-Crinane," Gary E. Keck and Robert R. Webb, II, J. Am. Chem. Soc. 1981, 103, 3173.
15. "Synthetic Studies on Pyrrolizidine Alkaloids. I. (±)-Heliotridine and (±)- Retronecine via Intramolecular Dienophile Transfer," Gary E. Keck and David G. Nickell, J. Am. Chem. Soc. 1980, 102, 3632.
14. "Allylic Amidation. An Investigation of Nitrosocarbonylmethane for Direct Allylic Functionalization of Olefins," Gary E. Keck and John B. Yates, Tetrahedron Lett. 1979, 4627.
13. "Carbon-Nitrogen Bond Formation via Acyl-Nitroso Compounds. Intramolecular Ene Processes," Gary E. Keck and Robret R. Webb II, Tetrahedron Lett. 1979, 1185.
12. "Stereochemistry of the Aryl-Vinyl Version of the Di-p-Methane Rearrangement," Howard E. Zimmerman, Thomas P. Gannett, and Gary E. Keck, J. Org. Chem. 1979, 44, 1982.
11. "Stereospecific Total Synthesis of Gibberellic Acid," E. J. Corey, Rick L. Danheiser, Srinivasan Chandrasekaran, Gary E. Keck, B. Gopalen, Sam D. Larsen, Patrice Siret, and Jean-Louie Gras, J. Am. Chem. Soc. 1978, 100, 8034.
10. "Stereospecific Total Synthesis of Gibberellic Acid. A Key Tricyclic Intermediate," E. J. Corey, Rick L. Danheiser, Srinivasan Chandrasekaran, Patrice Siret, Gary E. Keck, and Jean-Louie. Gras, J. Am. Chem. Soc. 1978, 100, 8031.
9. "Mild and Efficient Methods for the Reductive Cleavage of Nitrogen-Oxygen
Bonds," Gary E. Keck, Stephen A. Fleming, David Nickell, and Paul Weider, Synthetic Communications 1979, 9 (4), 281.
8. "Intramolecular Dienophile Transfer. Diels-Alder Adducts of Acyl-Nitroso Compounds as Useful Reagents for Intramolecular Cycloadditions," Gary E. Keck, Tetrahedron Lett. 1978, 47
7. "Model Studies on Narcissus Alkaloids. Synthetic Methodology for the Synthesis of Lycoricidine Analogues," Gary E. Keck and Stephen A. Fleming, Tetrahedron Lett. 1978, 4763.
6. "Stereochemistry in the Di-p-Methane Rearrangement; Aryl Migration. Exploratory and Mechanistic Organic Photochemistry," Howard E. Zimmerman, Thomas P. Gannett and Gary E. Keck, J. Am. Chem. Soc. 1978, 100, 323.
5. "Synthesis of Vane's Prostaglandin X, 6, 9a-Oxido-9a, 15a-dihydroxy-prosta-(Z)5, (E),13-dienoic Acid," E. J. Corey, Gary E. Keck, and Istvan Szekely, J. Am. Chem. Soc. 1977, 99, 2006.
4. "Independent Generation of Cyclopropyldicarbinyl Diradical Species of the Di-p-Methane Rearrangement. Excited Singlet, Triplet, and Ground State Hypersurfaces of Barrelene Photochemistry. Mechanistic and Exploratory Organic Photochemistry," Howard E. Zimmerman, Robert J. Boettcher, Neil E. Buehler, Gary E. Keck, and Mark J. Steinmetz, J. Am. Chem. Soc. 1976, 98, 7680.
3. "Molecular
Rearrangements of Excited States Generated by Intramolecular Dioxetane
Scission: Photochemistry Without Light. Mechanistic and Exploratory
Organic Photochemistry," Howard E. Zimmerman,
2. "Generation of Photochemical Species on Ground, Excited Singlet, and Triplet Hypersurfaces in Barrelene Photochemistry," Howard E. Zimmerman, Robert J. Boettcher, Neil E. Buehler, and Gary E. Keck, J. Am. Chem. Soc. 1975, 97, 5635.
1. "A Photochemical Rearrangement Without Light. Dioxetane Effected Photochemistry by Direct Intramolecular Excitation," Howard. E. Zimmerman and Gary E. Keck, J. Am. Chem. Soc. 1975, 97, 3527.