Professor Dale Poulter

Professor C. Dale Poulter

Education

  • B.S., 1964, Louisiana State University (Cum Laude)
  • Ph.D., 1967, University of California at Berkeley, with W.G. Dauben
  • Postdoctoral, 1967-69, University of California at Los Angeles, with S. Winstein

Contact

Office: HEB 2274

Phone: 801.581.6685

Email:poulter@chem.utah.edu

Awards

  • Honorary Professor, University of Queensland, Brisbande, Australia, 2002-2004
  • Repligen Award, Biological Division, American Chemical Society, 2002
  • Wilsmore Fellow, Melbourne University, 2001
  • Rosenblatt Award, University of Utah, 1999
  • Arthur C. Cope Scholar Award, American Chemical Society, 1998
  • Governor's Medal for Science and Technology, 1995
  • National Institutes of Health Merit Award, 1995
  • Fellow, American Association for the Advancement of Science, 1994
  • Utah Award, American Chemical Society, 1992
  • Ernest Guenther Award, American Chemical Society, 1991
  • Distinguished Research Award, University of Utah, 1984
  • David P. Gardner Faculty Fellow, 1983
  • Alfred P. Sloan Fellow, 1975-79
  • NIH Career Development Awardee, 1975-80
  • NIH Postdoctoral Fellow, 1967-69
  • NIH Predoctoral Fellow, 1965-67
  • Omnicron Delta Kappa, 1964
  • Phi Lambda Upsilon, 1964
  • Phi Kappa Phi, 1964

Professional Positions

  • Distinguished Professor of Chemistry, University of Utah, 1996-present
  • Chair, Department of Chemistry, University of Utah, 1995-2000
  • John A. Widtsoe Professor of Chemistry, University of Utah, 1994-present
  • Research Professor, Department of Medicinal Chemistry, University of Utah, 1978-present
  • Adjunct Professor, Department of Biochemistry, University of Utah, 1986-present
  • Professor, Department of Chemistry, University of Utah, 1978-1994
  • Director, Interdepartmental Program in Biological Chemistry, 1990-1993
  • Associate Professor, Department of Chemistry, University of Utah, 1975-1978
  • Associate Research Professor, Department of Biopharmaceutical Sciences, University of Utah, 1975-1978
  • Assistant Professor, Department of Chemistry, University of Utah, 1969-1975
  • Assistant Research Professor, Department of Biopharmaceutical Sciences, University of Utah, 1971-1975
  • Chemist, Esso Research Laboratory, Baton Rouge, Louisiana, Summer 1964
  • Chemist, PPG Chemicals, Lake Charles, Louisiana, Summers, 1962, 1963

Professional Activities

  • NAS, Bio2010, Chemistry sub-committee, 2001
  • AAAS, Member-at-Large, 2001-present
  • CS, Advisory Committee on Graduate Education, 2000-present
  • ACS, Committee on Professional Training, 1996-present
  • ACS, Councilor, Biological Division, 1993-present
  • AAAS, Nominating Committee Chemistry Division, 1997-1999, Chair 1999
  • ACS, Chair of Organic Division, 1998
  • ACS, Selection Committee; Editor of Organic Letters, 1998
  • ACS, Committee on Science, 1996-1999
  • NSF, Workshop on Organic Synthesis and Natural Products, co-organizer, 1993-1995
  • 14th Enzyme Mechanisms Conference, Scottsdale, AZ, Chair, 1993-95
  • 13th Enzyme Mechanisms Conference, Key Largo, FL, organizing committee, 1991-97
  • NIH, General Medical Sciences Council, 1990
  • ACS, American Coordinator, Biological Program, Pacific Basin Chemical Congress, 1989, 1995
  • PRF, Advisory Board, 1988-1990
  • ACS, Selection Committee; Editor of Journal of Organic Chemistry, 1988
  • ACS, Program Chairman for Biological Division, 1987
  • ACS, Canvassing Committee, Roger Adams Award in Organic Chemistry, 1986-1990
  • Gordon Conference on Enzymes, Coenzymes, and Metabolic Pathways, Chair, 1985
  • ACS, Executive Committee Organic Division, 1983-1986
  • NAS, Workshop on Effort Reporting Requirements of OMB Circular A-21; 1983
  • NIH, Ad Hoc member and Special Study Sections; 1980-1993
  • 7th Enzyme Mechanisms Conference; Sanibel, Florida; organizing committee, 1981-1983
  • ACS, Ad Hoc Task Force to monitor the Journal of Organic Chemistry; 1980-1981
  • NIH, Medicinal Chemistry A Study Section; 1977-81

Editorial Activities

  • Editor-in-Chief, Journal of Organic Chemistry, 2001- present
  • Senior Editor, Journal of Organic Chemistry, 2000-2001
  • Associate Editor, Organic Letters, 1999-2001
  • Associate Editor, Journal of Organic Chemistry, 1990-1995
  • Editorial Advisory Board, Chemical Reviews, 1996-2001
  • Editorial Advisory Board, Bioorganic & Medicinal Chemistry, 1993-present
  • Editorial Advisory Board, Journal of Organic Chemistry, 1987-1990
  • Editorial Board, Journal of Bioorganic Chemistry, 1983-1990
  • Editorial Advisory Board, Journal of the American Chemical Society, 1983-1986

Publications

  • Dauben, W.G.; Poulter, C.D. "The Addition of Methanol to Some Bicyclobutanes." Tetrahedron Lett., 1967, 3021-3025.
  • Dauben, W.G.; Poulter, C.D. "The Solvolysis of 1-Chlorobicyclo[3.3.1]nonane." J. Org. Chem., 1968, 33, 1237-1239.
  • Poulter, C.D.; Winstein, S. "The Cyclopropylcarbinyl-Allyl Rearrangement of a Hexamethyl-cyclopropylcarbinyl System." J. Am. Chem. Soc., 1969, 91, 3649-3650.
  • Poulter, C.D.; Winstein, S. "Solvolysis and Degenerate Cyclopropylcarbinyl-Cyclopropyl-carbinyl Rearrangement of a Hexamethylcyclopropylcarbinyl System." J. Am. Chem. Soc., 1969, 91, 3650-3652.
  • Poulter, C.D.; Friedrich, E.C.; Winstein, S. "The Stereochemistry of the Methylene Iodide-Zinc-Copper Couple Methylenation of Cyclic Allylic Alcohols." J. Am. Chem. Soc., 1969, 91, 6892-6894.
  • Poulter, C.D.; Friedrich, E.C.; Winstein, S. "Stereospecific Cationic Rearrangements of syn- and anti-Bicyclo[6.1.0]nonane Derivatives." J. Am. Chem. Soc., 1970, 92, 4274-4281.
  • Poulter, C.D.; Winstein, S. "Stereospecific Homoallylic Ring Expansions and Contractions." J. Am. Chem. Soc., 1970, 92, 4282-4288.
  • Dauben, W.G.; Poulter, C.D.; Suter, C. "Photoisomerizations of cis- and trans-3-Methylene-cyclodecene." J. Am. Chem. Soc., 1970, 92, 7408-7412.
  • Rilling, H.C.; Poulter, C.D.; Epstein, W.W.; Larsen, B. "Studies on the Mechanism of Squalene Biosynthesis. Presqualene Pyrophosphate, Stereochemistry and a Mechanism for Its Conver-sion to Squalene." J. Am. Chem. Soc., 1971, 93, 1783-1785.
  • Poulter, C.D.; Dickson, R.B. "Stereospecific 5J1H-1H and 6J1H-1H Couplings in 3-Methyl-3-azabicyclo [3.1.0]hexan-2,4-dione." Tetrahedron Lett., 1971, 2255-2258.
  • Poulter, C.D.; Boikess, R.S.; Brauman, J.I.; Winstein, S. "Shielding Effects of a Cyclopropane Ring." J. Am. Chem. Soc., 1972, 94, 2291-2296.
  • Poulter, C.D.; Winstein, S. "The a ,a ,2,2,3,3-Hexamethylcyclopropylcarbinyl System. A Study of Carbonium Ion Behavior in Nucleophilic and Superacid Solvents." J. Am. Chem. Soc., 1972, 94, 2297-2305.
  • Poulter, C.D.; Moesinger, S.G.; Epstein, W.W. "Solvolysis of N-Methyl-4-(chrysanthemyloxy) pyridinium Iodide--A Model for Non-Head-to-Tail Monoterpene Biosynthesis." Tetrahedron Lett., 1972, 67-70.
  • Poulter, C.D.; Goodfellow, R.J.; Epstein, W.W. "The Absolute Configuration of Santolina Alcohol from Ormenis multicaulis." Tetrahedron Lett., 1972, 71-74.
  • Poulter, C.D. "Model Studies of Terpene Biosynthesis. Stereoselective Ionization of N-Methyl-4-[(a S,1R,3R)-chrysanthemyloxy]pyridinium-d1 Iodide." J. Am. Chem. Soc., 1972, 94, 5515-5516.
  • Poulter, C.D.; Muscio, O.J.; Spillner, C.J.; Goodfellow, R.J. "Model Studies of Terpene Biosynthesis. Cationic Rearrangements Leading to Head-to-Head Terpenes." J. Am. Chem. Soc., 1972, 94, 5921-5923.
  • Poulter, C.D.; Anderson, R.B. "Direct Observation of Uracil Dication and Related Derivatives." Tetrahedron Lett., 1972, 3823-3826.
  • Epstein, W.W.; Poulter, C.D. "A Survey of Some Irregular Monoterpenes and their Biogenetic Analogies to Presqualene Alcohol." Phytochemistry, 1973, 12, 737-747.
  • Poulter, C.D. "Model Studies in Terpene Biosynthesis." Agric. and Food Chem., 1974, 22, 167-173.
  • Poulter, C.D.; Muscio, O.J.; Goodfellow, R.J. "Biosynthesis of Head-to-Head Terpenes. Carbonium Ion Rearrangements Which Lead to Head-to-Head Terpenes." Biochemistry, 1974, 13, 1530-1538.
  • Muscio, O.J.; Poulter, C.D. "Model Studies in Terpene Biosynthesis. Synthesis and Absolute Configuration of (+)-trans-2,2-Dimethyl-3-(2'-methyl-propenyl)cyclobutanol." J. Org. Chem., 1974, 39, 3288-3291.
  • Poulter, C.D.; Spillner, C.J. "The (trans-2'-Methylcyclopropyl)methyl System. Stereochemistry of Ionization, Rearrangement, and Solvent Capture." J. Am. Chem. Soc., 1974, 96, 7591-7593.
  • Poulter, C.D.; Muscio, O.J.; Goodfellow, R.J. "Model Studies of Terpene Biosynthesis. Synthesis of (+)-2-[trans-2'-(2'-Methylpropenyl)cyclopropyl]propan-2-ol." J. Org. Chem., 1975, 40, 139-140.
  • Frederick, G.D.; Poulter, C.D. "Extension of the HA Acidity Function into Oleum Mixtures." J. Am. Chem. Soc., 1975, 97, 1797-1801.
  • Poulter, C.D.; Frederick, G.D. "Uracil and its 4-Hydroxy-1(H) and 2-Hydroxy-3(H) Protomers. pKa's and Equilibrium Constants." Tetrahedron Lett., 1975, 2171-2174.
  • Spicer, L.D.; Poulter, C.D. "Isotopes as Probes for Determining Reaction Mechanisms." In Physical Chemistry. An Advanced Treatise; Vol. 7, H. Eyring, D. Henderson, W. Jost, Ed.; Academic Press: 1975.
  • Epstein, W.W.; McGee, L.R.; Poulter, C.D.; Marsh, L.L. "Mass Spectral Data for Gas Chromatograph--Mass Spectral Identification of Some Irregular Monoterpenes." J. Chem. and Engr. Data, 1976, 21, 500-502.
  • Poulter, C.D.; Rilling, H.C. "Prenyltransferase. The Mechanism of the Reaction." Biochemistry, 1976, 15, 1079-1083.
  • Poulter, C.D.; Satterwhite, D.M.; Rilling, H.C. "Prenyltransferase. The Mechanism of the Reaction." J. Am. Chem. Soc., 1976, 98, 3376-3377.
  • Poulter, C.D.; Argyle, J.C.; Mash, E.A. "Prenyltransferase. New Evidence for an Ionization-Condensation-Elimination Mechanism with 2-Fluorogeranyl Pyrophos-phate." J. Am. Chem. Soc., 1977, 99, 957-959.
  • Poulter, C.D.; Marsh, L.L.; Hughes, J.M.; Argyle, J.C.; Satterwhite, D.M.; Goodfellow, R.J.; Moesinger, S.G. "Model Studies of the Biosynthesis of Non-Head-to-Tail Terpenes. Rear-rangements of the Chrysanthemyl System." J. Am. Chem. Soc., 1977, 99, 3816-3823.
  • Poulter, C.D.; Hughes, J.M. "Model Studies of the Biosynthesis of Non-Head-to-Tail Terpenes. Stereochemistry of Ionization for N-Methyl-4-[(1S,1'R,3'R)-[1-2H]Chrysanthemyloxy]pyridinium Iodide." J. Am. Chem. Soc., 1977, 99, 3824-3829.
  • Poulter, C.D.; Hughes, J.M. "Model Studies of the Biosynthesis of Non-Head-to-Tail Terpenes. Stereochemistry of the Head-to-Head Rearrangement." J. Am. Chem. Soc., 1977, 99, 3830-3837.
  • Roberts, J.L.; Borromeo, P.S.; Poulter, C.D. "Addition of Grignard and Lithium Reagents to Eschenmoser's Salt. A Convenient Synthesis of Terminal Olefins." Tetrahedron Lett., 1977, 1299-1302.
  • Roberts, J.L.; Borromeo, P.S.; Poulter, C.D. "Addition of Eschenmoser's Salt to Ketone, Ester, and Lactone Enolates. A Convenient Synthesis of a -Methylene Carbonyls via Mannich Intermediates." Tetrahedron Lett., 1977, 1621-1624.
  • Poulter, C.D.; Satterwhite, D.M. "Mechanism of the Prenyl Transfer Reaction. Studies with (E)- and (Z)-3-Trifluoromethyl-2-buten-1-yl Pyrophosphate." Biochemistry, 1977, 16, 5470-5478.
  • Roberts, J.L.; Poulter, C.D. "2',3',5'-Tri-O-benzoyl[4-13C]uridine. An Efficient, Regiospecific Synthesis of the Pyrimidine Ring." J. Org. Chem., 1978, 43, 1547-1550.
  • Teranishi, R.; Flath, R.A.; Mon, T.R.; Poulter, C.D.; Kikuchi, M. "Volatile Constituents of California Sage Brush." Fragrance J., 1978, 6, 45-47.
  • Poulter, C.D.; Argyle, J.C.; Mash, E.A. "Farnesyl Pyrophosphate Synthetase. Mechanistic Studies of the 1'-4 Coupling Reaction with 2-Fluorogeranyl Pyrophosphate." J. Biol. Chem., 1978, 253, 7227-7233.
  • Poulter, C.D.; Rilling, H.C. "The Prenyl Transfer Reaction. Enzymatic and Mechanistic Studies of the 1'-4 Coupling Reaction in the Terpene Biosynthetic Pathway." Acc. Chem. Res., 1978, 11, 307-313.
  • Poulter, C.D.; Livingston, C.L. "[3-15N]-2',3',5'-Tri-O-benzoyluridine. Detection of Hydrogen Bonding in A-U Base Pairs by 15N NMR." Tetrahedron Lett., 1979, 755-758.
  • Gaughan, R.G.; Poulter, C.D. "Non-Head-to-Tail Monoterpenes. Synthesis of (S)-Lyratol and (S)-Lyratyl Acetate from (1R,3R)-Chrysanthemic Acid." J. Org. Chem., 1979, 44, 2441-2444.
  • Laskovics, F.M.; Krafcik, J.M.; Poulter, C.D. "Prenyltransferase. Kinetic Studies of the 1'-4 Coupling Reaction with Avian Liver Enzyme." J. Biol. Chem., 1979, 254, 9458-9463.
  • Poulter, C.D.; Mash, E.A.; Argyle, J.C.; Muscio, O.J.; Rilling, H.C. "Farnesyl Pyrophosphate Synthetase. Mechanistic Studies of the 1'-4 Coupling Reaction in the Terpene Biosynthetic Pathway." J. Am. Chem. Soc., 1979, 101, 6761-6763.
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